Search on: HIV PROTEINASE 
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Descriptor English:   HIV Protease 
Descriptor Spanish:   Proteasa del VIH 
Descriptor Portuguese:   Protease de HIV 
Synonyms English:   p16 pol gene product, HIV
p16 protease, HIV
HIV p16 protease
HTLV III Protease
Protease, HIV
Protease, HTLV-III
HIV Proteinase
HTLV-III Protease  
Tree Number:   D08.811.277.656.074.500.340
D08.811.277.656.300.048.340
D12.776.964.775.375.545.750
Definition English:   Enzyme of the human immunodeficiency virus that is required for post-translational cleavage of gag and gag-pol precursor polyproteins into functional products needed for viral assembly. HIV protease is an aspartic protease encoded by the amino terminus of the pol gene. 
Entry Combination - descr/qualif English:   HIV Protease/antagonists & inhibitors use HIV Protease Inhibitors
 
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   28981 
Unique Identifier:   D016333 

Occurrence in VHL:
 

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